Product Overview Generic name: Fluocinolone Acetonide + Hydroquinone + Tretinoin Brand name: Sofit Strength / Size: 15 g cream Manufacturer: Global Pharmaceuticals ⚙️ Mechanism of Action Fluocinolone Acetonide → Mild corticosteroid; reduces inflammation and irritation. Hydroquinone → Inhibits melanin synthesis by blocking tyrosinase enzyme. Tretinoin → Promotes skin cell turnover, enhances penetration of hydroquinone, and reduces pigmentation. 🩺 Clinical Uses Melasma → Reduces dark patches on face caused by hormonal changes or sun exposure. Hyperpigmentation → Treats localized dark spots and uneven skin tone. Combination therapy → Provides synergistic effect for faster and more effective results. ⚠️ Side Effects Common: Mild redness, peeling, dryness, burning sensation. Moderate: Skin irritation, sensitivity to sunlight. Serious (rare): Allergic reaction, severe skin thinning with prolonged use. 🔒 Precautions For external use only; apply thinly to affected areas. Avoid contact with eyes, mouth, and mucous membranes. Use sunscreen during treatment to prevent recurrence. Not recommended during pregnancy or breastfeeding without medical advice. Store below 30°C, away from direct sunlight. 👩‍⚕️ Patient Counselling Points Apply once daily at night or as directed by physician. Wash and dry face before application. Use sunscreen during the day to prevent worsening of melasma. Do not use for longer than prescribed (usually 8 weeks). Report persistent irritation or allergic reactions to healthcare provider.